Set Against the backdrop of a clubhouse, former baseball player Joe DiMaggio would engage his studio audiences and his viewers in a sports quiz and teach them the pointers of playing sports properly (via films that He would provide off camera narrations). Often, well known sports figures would make guest appearances on the program. Radio/ tv broadcaster and game show host and creator Jack Barry would serve as the show's announcer and commercial spokesman.
"The Joe DiMaggio Show" was seen in prime time on The NBC TV Network From 1950 until 1951. A radio version of "The Joe DiMaggio Show" was heard on The NBC Radio Network during the early 1950's. Former boxer turned singer and actor Frank Sinatra appeared on The NBC Radio Network version of the program.